USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: P35237 USC-OGP 2-DE database:  P35237 P35237 General information about the entry View entry in simple text format Entry name SPB6_HUMAN Primary accession number P35237 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Serpin B6; AltName: Full=Cytoplasmic antiproteinase; Short=CAP; AltName: Full=Peptidase inhibitor 6; Short=PI-6; AltName: Full=Placental thrombin inhibitor;. Gene name Name=SERPINB6 Synonyms=PI6, PTI Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0705: pI=5.28; Mw=43115 Cross-references UniProtKB/Swiss-Prot P35237; SPB6_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name SPB6_HUMAN Primary accession number P35237 Secondary accession number(s) B2RBA8 Q59F97 Q5TD06 Q7Z2Y7 Q96J44 Q9UDI7 Sequence was last modified on  December 4, 2007 (version 3) Annotations were last modified on  March 15, 2017 (version 167) Name and origin of the protein Description RecName: Full=Serpin B6; AltName: Full=Cytoplasmic antiproteinase; Short=CAP; AltName: Full=Peptidase inhibitor 6; Short=PI-6; AltName: Full=Placental thrombin inhibitor; Gene name Name=SERPINB6 Synonyms=PI6, PTI Encoded on Name=SERPINB6; Synonyms=PI6, PTI Keywords Acetylation; Complete proteome; Cytoplasm; Deafness; Direct protein sequencing; Non-syndromic deafness; Phosphoprotein; Polymorphism; Protease inhibitor; Reference proteome; Serine protease inhibitor. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL Z22658; CAA80373.1; -; mRNA EMBL S69272; AAB30320.1; -; mRNA EMBL AK314578; BAG37155.1; -; mRNA EMBL BX538343; CAD98106.1; ALT_INIT; mRNA EMBL AL133351; CAI23292.1; -; Genomic_DNA EMBL CH471087; EAW55097.1; -; Genomic_DNA EMBL BC001394; AAH01394.1; -; mRNA EMBL BC098564; AAH98564.1; -; mRNA EMBL AB209563; BAD92800.1; ALT_INIT; mRNA CCDS CCDS4479.1; -; . PIR A48681; A48681; . RefSeq NP_001182220.2; NM_001195291.2; . RefSeq NP_001258751.1; NM_001271822.1; . RefSeq NP_001258752.1; NM_001271823.1; . RefSeq NP_001258753.1; NM_001271824.1; . RefSeq NP_001258754.1; NM_001271825.1; . RefSeq NP_001284628.1; NM_001297699.1; . RefSeq NP_001284629.1; NM_001297700.1; . RefSeq NP_004559.4; NM_004568.5; . RefSeq XP_011512975.1; XM_011514673.1; . RefSeq XP_011512976.1; XM_011514674.2; . UniGene Hs.519523; -; . UniGene Hs.731506; -; . ProteinModelPortal P35237; -; . SMR P35237; -; . BioGrid 111287; 13; . IntAct P35237; 1; . MINT MINT-5005332; -; . STRING 9606.ENSP00000338358; -; . DrugBank DB00055; Drotrecogin alfa; . MEROPS I04.011; -; . iPTMnet P35237; -; . PhosphoSitePlus P35237; -; . SwissPalm P35237; -; . BioMuta SERPINB6; -; . DMDM 161784343; -; . OGP P35237; -; . EPD P35237; -; . MaxQB P35237; -; . PaxDb P35237; -; . PeptideAtlas P35237; -; . PRIDE P35237; -; . DNASU 5269; -; . Ensembl ENST00000335686; ENSP00000338358; ENSG00000124570; . Ensembl ENST00000380520; ENSP00000369891; ENSG00000124570; . Ensembl ENST00000380524; ENSP00000369896; ENSG00000124570; . Ensembl ENST00000380529; ENSP00000369901; ENSG00000124570; . Ensembl ENST00000380539; ENSP00000369912; ENSG00000124570; . Ensembl ENST00000380546; ENSP00000369919; ENSG00000124570; . GeneID 5269; -; . KEGG hsa:5269; -; . UCSC uc003muk.3; human; . CTD 5269; -; . DisGeNET 5269; -; . GeneCards SERPINB6; -; . H-InvDB HIX0005534; -; . HGNC HGNC:8950; SERPINB6; . HPA HPA009668; -; . HPA HPA012736; -; . MalaCards SERPINB6; -; . MIM 173321; gene; . MIM 613453; phenotype; . neXtProt NX_P35237; -; . OpenTargets ENSG00000124570; -; . Orphanet 90636; Autosomal recessive non-syndromic sensorineural deafness type DFNB; . PharmGKB PA35516; -; . eggNOG KOG2392; Eukaryota; . eggNOG COG4826; LUCA; . GeneTree ENSGT00760000118789; -; . HOGENOM HOG000238519; -; . HOVERGEN HBG005957; -; . InParanoid P35237; -; . KO K13963; -; . PhylomeDB P35237; -; . TreeFam TF352619; -; . Reactome R-HSA-6798695; Neutrophil degranulation; . Reactome R-HSA-75205; Dissolution of Fibrin Clot; . ChiTaRS SERPINB6; human; . GeneWiki SERPINB6; -; . GenomeRNAi 5269; -; . PRO PR:P35237; -; . Proteomes UP000005640; Chromosome 6; . Bgee ENSG00000124570; -; . CleanEx HS_SERPINB6; -; . ExpressionAtlas P35237; baseline and differential; . Genevisible P35237; HS; . GO GO:0005737; C:cytoplasm; IDA:UniProtKB; . GO GO:0005829; C:cytosol; TAS:ProtInc; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005615; C:extracellular space; IBA:GO_Central; . GO GO:0101003; C:ficolin-1-rich granule membrane; TAS:Reactome; . GO GO:0005886; C:plasma membrane; TAS:Reactome; . GO GO:0043234; C:protein complex; IDA:BHF-UCL; . GO GO:0030667; C:secretory granule membrane; TAS:Reactome; . GO GO:0070821; C:tertiary granule membrane; TAS:Reactome; . GO GO:0002020; F:protease binding; IPI:UniProtKB; . GO GO:0004867; F:serine-type endopeptidase inhibitor activity; IDA:BHF-UCL; . GO GO:0071470; P:cellular response to osmotic stress; IMP:UniProtKB; . GO GO:0010951; P:negative regulation of endopeptidase activity; IDA:BHF-UCL; . GO GO:0043312; P:neutrophil degranulation; TAS:Reactome; . GO GO:0007605; P:sensory perception of sound; IMP:UniProtKB; . InterPro IPR023795; Serpin_CS; . InterPro IPR023796; Serpin_dom; . InterPro IPR000215; Serpin_fam; . PANTHER PTHR11461; PTHR11461; 1; . Pfam PF00079; Serpin; 1; . SMART SM00093; SERPIN; 1; . SUPFAM SSF56574; SSF56574; 1; . PROSITE PS00284; SERPIN; 1; .

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